Medical Laboratory Manager

Company: CURESPONSE
Location: Philadelphia
Posted on: January 28, 2026

Job Description:

Job Description CURESPONSE Precision Oncology | Functional Drug Sensitivity Testing CLINICAL LABORATORY MANAGER Location: Philadelphia, PA | Employment Type: Full-Time About Curesponse Curesponse is a pioneering precision oncology company revolutionizing cancer treatment through our proprietary cResponse™ functional drug sensitivity platform. Our technology enables personalized treatment selection by testing patient-derived tumor samples against multiple therapeutic options, empowering oncologists to make data-driven treatment decisions. We are establishing our first U.S. clinical laboratory in Philadelphia to bring this transformative technology closer to American patients and healthcare providers. Position Overview We are seeking an experienced Clinical Laboratory Manager to lead the establishment and operation of a new CLIA-certified clinical laboratory in the Philadelphia area. This is a foundational leadership role with the unique opportunity to build our U.S. laboratory operations from the ground up—including facility setup, equipment procurement, team recruitment, and achieving regulatory certification. The ideal candidate will combine hands-on technical expertise in histology and molecular genomics with strong operational and people leadership skills. Key Responsibilities Laboratory Setup & Establishment • Lead the end-to-end setup of the new clinical laboratory facility, from site selection through operational launch • Develop laboratory design specifications and work with architects/contractors to ensure optimal workflow and regulatory compliance • Manage equipment procurement, installation, validation, and qualification (IQ/OQ/PQ) • Establish relationships with key vendors and negotiate contracts for equipment, reagents, and supplies • Develop and implement Laboratory Information Management System (LIMS) and integrate with company systems • Create comprehensive standard operating procedures (SOPs) for all laboratory processes • Develop project timelines and budgets for laboratory establishment; track and report progress to leadership Team Building & Recruitment • Define staffing requirements and organizational structure for the laboratory team • Lead recruitment efforts to build a high-performing team of laboratory scientists, technicians, and support staff • Develop job descriptions, conduct interviews, and make hiring decisions for all laboratory positions • Create and implement comprehensive onboarding and training programs for new hires • Establish competency assessment protocols and ongoing professional development programs • Foster a collaborative, quality-focused laboratory culture aligned with company values • Manage performance evaluations, coaching, and career development for team members Laboratory Operations & Management • Oversee daily operations of the clinical laboratory, ensuring efficient workflow and high-quality output • Manage laboratory scheduling, workload distribution, and resource allocation • Oversee inventory management, equipment maintenance, and vendor relationships • Establish and monitor key performance indicators (KPIs) for laboratory operations • Manage laboratory budget and control operational costs Regulatory Compliance & Quality Assurance • Lead CLIA certification process and maintain ongoing compliance with CLIA, CAP, and state regulatory requirements • Develop, implement, and maintain a comprehensive quality management system • Ensure compliance with Pennsylvania state laboratory licensing requirements • Prepare for and manage regulatory inspections and audits • Oversee proficiency testing programs and corrective action procedures • Maintain documentation and records in accordance with regulatory standards Technical Leadership • Provide expertise in histology techniques including tissue processing, embedding, sectioning, and staining • Oversee molecular genomics workflows including nucleic acid extraction, library preparation, and sequencing • Validate and implement new assays and methodologies • Ensure accurate and timely reporting of test results • Collaborate with R&D to optimize the cResponse™ platform for clinical applications Required Qualifications • Prior degree and certification to direct a CLIA lab (e.g ASCP as MLS or Ph.D etc) • Minimum 3 years of clinical laboratory experience • Demonstrated experience with CLIA certification and compliance processes • Strong background in histology/histopathology techniques • Experience with molecular genomics methodologies (NGS, PCR, sequencing technologies) • Proven track record of building and leading high-performing teams • Experience recruiting, hiring, and developing laboratory personnel • Knowledge of Pennsylvania state laboratory regulations • Experience with Laboratory Information Management Systems (LIMS) • Excellent leadership, communication, and organizational skills Preferred Qualifications • Previous experience in a supervisory/management role in a clinical laboratory • Prior experience establishing a new laboratory facility or achieving initial CLIA certification • Experience in oncology-focused or specialized reference laboratories • Track record of successful laboratory build-out projects including facility design and equipment procurement • CAP inspection experience • Knowledge of functional drug sensitivity testing or ex-vivo tumor models • Experience working with academic medical centers or research institutions • Familiarity with precision medicine and companion diagnostics • Project management certification (PMP) or equivalent experience What We Offer • Rare opportunity to build and shape a cutting-edge precision oncology laboratory from inception • Competitive salary commensurate with experience • Equity participation in a growth-stage company • Flexible work arrangements • Professional development opportunities • Collaborative, mission-driven work environment How to Apply Qualified candidates should submit their resume and cover letter to Dr. Vered Bar at Vered@Curesponse.tech .Please include any relevant certifications. Curesponse is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

Keywords: CURESPONSE, Lakewood , Medical Laboratory Manager, Healthcare , Philadelphia, New Jersey